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Diastereoselective Ce(O i Pr) 3 ‐Catalyzed Pinacol Couplings of Aldehydes
Author(s) -
Groth Ulrich,
Jeske Mario
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(20000204)39:3<574::aid-anie574>3.0.co;2-o
Subject(s) - pinacol , catalysis , cerium , alkyl , aryl , chemistry , coupling (piping) , coupling reaction , aldehyde , organic chemistry , medicinal chemistry , materials science , metallurgy
Aliphatic aldehydes as well as aromatic aldehydes can be converted by means of cerium‐catalyzed pinacol coupling [Eq. (1)]. The coupling reaction products can be isolated with good to very good diastereoselectivities in favor of rac isomers ( rac : meso >88:12). R=alkyl, aryl.