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A New Synthetic Route to Unsymmetrical 1,2‐Bis(phosphanyl)ethanes and 1,2‐Arsanyl(phosphanyl)ethanes with and without a Stereogenic Center
Author(s) -
Fries Guido,
Wolf Justin,
Pfeiffer Matthias,
Stalke Dietmar,
Werner Helmut
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(20000204)39:3<564::aid-anie564>3.0.co;2-s
Subject(s) - stereocenter , chemistry , yield (engineering) , alkyl , medicinal chemistry , center (category theory) , sulfate , organic chemistry , catalysis , enantioselective synthesis , materials science , metallurgy , crystallography
A one‐pot reaction affords unsymmetrical 1,2‐bis(phosphanyl)ethanes 2 and 1,2‐arsanyl(phosphanyl)ethanes 3 from the cyclic sulfate 1 in high yield. Similarly, chiral 1,2‐bis(phosphanyl)ethanes and 1,3‐bis(phosphanyl)propanes could be obtained in enantiomerically pure form. R, R′=alkyl, phenyl.