Premium
X‐Ray, Molecular Diffusion, and NOESY NMR Studies of Chiral, Tetranuclear Cu I Catalysts Based on Monodentate Thiol Analogues of TADDOL
Author(s) -
Pichota Arkadius,
Pregosin Paul S.,
Valentini Massimiliano,
Wörle Michael,
Seebach Dieter
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(20000103)39:1<153::aid-anie153>3.0.co;2-n
Subject(s) - denticity , two dimensional nuclear magnetic resonance spectroscopy , thiol , chemistry , crystallography , catalysis , stereochemistry , organic chemistry , crystal structure
The new, stable, chiral thiol‐TADDOL Cu I catalysts 1 (X=OH, OMe, NMe 2 ) reveal an unexpected monodentate complexation mode, both in solution and in the solid state. For the first time, the aggregation state of organocopper complexes has been determined by NMR diffusion measurements. NOESY NMR data on model isocyanide Cu complexes reveal a different conformation of the TADDOL moiety as a function of the second potential donor group. TADDOL= α , α , α ′, α ′‐tetraaryl‐2,2‐dimethyl‐1,3‐dioxolane‐4,5‐dimethanol.