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Selective Homogeneous Palladium( 0 )‐Catalyzed Hydrogenation of Alkynes to ( Z )‐Alkenes
Author(s) -
van Laren Martijn W.,
Elsevier Cornelis J.
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19991216)38:24<3715::aid-anie3715>3.0.co;2-o
Subject(s) - palladium , catalysis , homogeneous , chemistry , stereoselectivity , homogeneous catalysis , aryl , denticity , acenaphthene , alkyne , organic chemistry , catalytic hydrogenation , medicinal chemistry , alkene , combinatorial chemistry , metal , alkyl , physics , thermodynamics , pyrene
Zero‐valent palladium precatalysts containing rigid bidentate bis(arylimino)acenaphthene ligands (shown schematically) facilitate the highly stereoselective homogeneous catalytic hydrogenation of alkynes to ( Z )‐alkenes. Internal, terminal, aryl‐substituted, and cyclic alkynes are suitable substrates, as are some enynes, which are chemoselectively hydrogenated to dienes. E=CO 2 Me; R 1 , R 2 =4‐OCH 3 , 4‐CH 3 , 2,6‐(CH 3 ) 2 .