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Membrane Anchoring and Intervesicle Transfer of a Derivative of the Antibiotic Moenomycin A
Author(s) -
Anikin Alexej,
Buchynskyy Andrij,
Kempin Uwe,
Stembera Katka,
Welzel Peter,
Lantzsch Gabriela
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19991216)38:24<3703::aid-anie3703>3.0.co;2-1
Subject(s) - anchoring , derivative (finance) , membrane , chemistry , biophysics , kinetics , biochemistry , biology , physics , structural engineering , quantum mechanics , financial economics , engineering , economics
The anchoring of moenomycin A (1) to the bacterial cell cytoplasmic membrane is essential for its biological activity. The first details of the strength of this interaction and the kinetics of the diffusion‐mediated intervesicle transfer have been obtained by means of fluorescence spectroscopic methods using a coumarin‐labeled moenomycin A derivative.