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Towards Efficient and Wide‐Scope Metal‐Catalyzed Alkyl–Alkyl Cross‐Coupling Reactions
Author(s) -
Cárdenas Diego J.
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19991018)38:20<3018::aid-anie3018>3.0.co;2-f
Subject(s) - alkyl , catalysis , coupling reaction , chemistry , alkane , metal , molecule , combinatorial chemistry , scope (computer science) , coupling (piping) , organic chemistry , materials science , computer science , metallurgy , programming language
The simplest organic fragment , C(sp 3 )−C(sp 3 ) , is unfortunately the most difficult to prepare by metal‐catalyzed cross‐coupling reactions (shown schematically) in the presence of functional groups. Recent advances show, however, that alkane moieties can be built within functionalized molecules by a careful choice of catalysts and conditions.