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An Effective Fluorescent Sensor for Choline‐Containing Phospholipids
Author(s) -
Tomàs Salvador,
Prohens Rafel,
Deslongchamps Ghislain,
Ballester Pablo,
Costa Antoni
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990802)38:15<2208::aid-anie2208>3.0.co;2-9
Subject(s) - fluorescence , squaramide , choline , chemistry , receptor , alkyl , ion , stereochemistry , supramolecular chemistry , molecule , biochemistry , organic chemistry , enantioselective synthesis , physics , quantum mechanics , organocatalysis , catalysis
A set of weak CH⋅⋅⋅O interactions is responsible for the recognition of tetraalkylammonium ions (ball‐and‐stick structure) by the tripodal receptors depicted in the diagram, in which the binding pocket is lined with squaramide units. The association constants of the fluorescent receptors are remarkably high at about 10 5 M −1 and can be used for signaling the presence of selected choline phospholipids. Z=RNH, where R=alkyl, arylamino; X − =BH 4 − , Cl − , Br − , I − .