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Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics
Author(s) -
Nicolaou K. C.,
Boddy Christopher N. C.,
Bräse Stefan,
Winssinger Nicolas
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990802)38:15<2096::aid-anie2096>3.0.co;2-f
Subject(s) - glycopeptide , antibiotics , vancomycin , glycopeptide antibiotic , bacteria , microbiology and biotechnology , biology , chemistry , staphylococcus aureus , genetics
The war against infectious bacteria is not over! Although vancomycin and glycopeptide antibiotics have provided a strong last line of defence against many drug‐resistant bacteria, their overuse has given rise to more dangerous strains of bacteria. An understanding of the chemistry and biology of these highly complex glycopeptides are destined to play a crucial role in the discovery of new antibiotics.