Premium
Synthesis and Characterization of a Unimolecular Capsule
Author(s) -
Brody Marcus S.,
Schalley Christoph A.,
Rudkevich Dmitry M.,
Rebek, Jr. Julius
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990601)38:11<1640::aid-anie1640>3.0.co;2-y
Subject(s) - dimer , chemistry , molecule , solvent , characterization (materials science) , mass spectrometry , polymer chemistry , electrospray mass spectrometry , urea , nuclear magnetic resonance spectroscopy , crystallography , computational chemistry , electrospray , stereochemistry , organic chemistry , materials science , nanotechnology , chromatography
There is more than one way to assemble the two halves of a tethered, urea‐substituted calix[4]arene dimer (shown schematically): formation of unimolecular capsules (far left), dimers, or oligomers. By combination of NMR spectroscopy and electrospray mass spectrometry, a hexamethylene spacer was shown to be exactly right to permit the preferential formation of a unimolecular capsule under inclusion of solvent or other guest molecules.