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Sphingolipids—Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases
Author(s) -
Kolter Thomas,
Sandhoff Konrad
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990601)38:11<1532::aid-anie1532>3.0.co;2-u
Subject(s) - sphingolipid , glycolipid , signal transduction , metabolic pathway , microbiology and biotechnology , ceramide , ganglioside , neuroscience , biology , biochemistry , computational biology , chemistry , metabolism , apoptosis
Glycolipids such as ganglioside GM1 are involved in the building of carbohydrate layers on the surface of living cells. The investigation of the metabolism of this class of compounds gives insight into human diseases, novel signal transduction processes, and the epidermal water permeability barrier.