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Topological Links between Duplex DNA and a Circular DNA Single Strand
Author(s) -
Kuhn Heiko,
Demidov Vadim V.,
FrankKamenetskii Maxim D.
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990517)38:10<1446::aid-anie1446>3.0.co;2-3
Subject(s) - dna , oligonucleotide , nucleic acid , duplex (building) , dna origami , catenane , dna nanotechnology , topology (electrical circuits) , computational biology , biology , physics , genetics , mathematics , combinatorics , quantum mechanics , molecule
DNA nanostructures of building blocks topologically linked at a precise position can be assembled from DNA duplexes and circularized oligonucleotides with the aid of peptide nucleic acids (PNAs). Shown schematically is a linked catenane yielding an earring topological DNA label.