Premium
On the Mechanism of Long‐Range Electron Transfer through DNA
Author(s) -
Giese Bernd,
Wessely Stephan,
Spormann Martin,
Lindemann Ute,
Meggers Eric,
MichelBeyerle Maria E.
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990401)38:7<996::aid-anie996>3.0.co;2-4
Subject(s) - mechanism (biology) , range (aeronautics) , dna , electron transfer , biophysics , chemical physics , chemistry , materials science , physics , biology , photochemistry , biochemistry , quantum mechanics , composite material
Hopping between bases of similar redox potentials is the mechanism by which charge transport occurs through DNA. This was shown by rate measurements performed with double strands 1 – 3 . This mechanism explains why hole transfer displays a strong sequence dependence, and postulates that electron transfer in unperturbed DNA should not be dependent on the sequence.