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A Chelate with Conformational Memory?
Author(s) -
Alonso M. Aránzazu,
Casares Juan A.,
Espinet Pablo,
Soulantica Katerina
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990215)38:4<533::aid-anie533>3.0.co;2-f
Subject(s) - chirality (physics) , reagent , chelation , group (periodic table) , chemistry , regular polygon , stereochemistry , physics , chiral symmetry , mathematics , organic chemistry , geometry , quark , quantum mechanics , nambu–jona lasinio model
Coordinated out, pendant in! Exchange of coordinated for pendant amino groups is achieved by the complex cation 1 . The incoming group attacks the concave and convex positions with the same rate and always adopts the same conformation as the leaving group. However, this “conformational memory” is an inexorable consequence of well‐known and dependable concepts: the principle of microscopic reversibility and the induction of chirality in prochiral reagents.