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High‐Throughput Synthesis and Screening of Combinatorial Heterogeneous Catalyst Libraries
Author(s) -
Cong Peijun,
Doolen Robert D.,
Fan Qun,
Giaquinta Daniel M.,
Guan Shenheng,
McFarland Eric W.,
Poojary Damodara M.,
Self Kyle,
Turner Howard W.,
Weinberg W. Henry
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990215)38:4<483::aid-anie483>3.0.co;2-#
Subject(s) - high throughput screening , throughput , catalysis , combinatorial chemistry , chemistry , nanotechnology , computer science , organic chemistry , materials science , biochemistry , telecommunications , wireless
In less than one minute the catalytic activity and selectivity of a single catalyst was measured in combinatorial libraries of ternary Rh‐Pd‐Pt‐Cu alloys. Only slightly more than two hours were needed to complete a library with 136 elements. The elements of the libraries (ca. 2–4 μg of material) are contained in a two‐dimensional array synthesized by a thin‐film technique. The analysis was performed by a scanning mass spectrometer (see picture).