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Nickel‐Catalyzed Homoallylation of Aldehydes and Ketones with 1,3‐Dienes and Complementary Promotion by Diethylzinc or Triethylborane
Author(s) -
Kimura Masanari,
Fujimatsu Hidetaka,
Ezoe Akihiro,
Shibata Kazufumi,
Shimizu Masamichi,
Matsumoto Satoru,
Tamaru Yoshinao
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990201)38:3<397::aid-anie397>3.0.co;2-y
Subject(s) - triethylborane , diethylzinc , catalysis , nickel , chemistry , promotion (chess) , organic chemistry , enantioselective synthesis , political science , politics , law
Regio‐ and stereoselective homoallylation of saturated aldehydes and ketones to give bishomoallyl alcohols 1,3‐ anti ‐ 1 is achieved with [Ni(acac) 2 ] (cat.) and Et 2 Zn [Eq. (a)]. This new catalyst system thus complements the previously reported combination of [Ni(acac) 2 ] with Et 3 B, which offers advantages in the homoallylation of unsaturated and aromatic aldehydes. acac=acetylacetonato.