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Amphiphilic p‐tert ‐Butylcalix[4]arene Scaffolds Containing Exposed Carbohydrate Dendrons
Author(s) -
Roy René,
Kim Jin Mi
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990201)38:3<369::aid-anie369>3.0.co;2-1
Subject(s) - amphiphile , dendrimer , calixarene , monolayer , chemistry , molecule , polystyrene , carbohydrate , scaffold , amphiphilic molecule , micelle , polymer chemistry , stereochemistry , biophysics , combinatorial chemistry , organic chemistry , biochemistry , polymer , copolymer , biomedical engineering , medicine , aqueous solution , biology
The best of both worlds. Amphiphilic hybrid molecules, in which water‐exposed glycodendrons are attached to a hydrophobic p‐tert ‐butylcalix[4]arene scaffold, display strong affinities for both carbohydrate‐binding proteins and polystyrene surfaces (shown schematically). The molecules can form monolayers useful in bioanalytical devices.