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Supramolecular Catalysis of Ester and Amide Cleavage by a Dinuclear Barium( II ) Complex
Author(s) -
Cacciapaglia Roberta,
Di Stefano Stefano,
Kelderman Erik,
Mandolini Luigi
Publication year - 1999
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19990201)38:3<348::aid-anie348>3.0.co;2-d
Subject(s) - moiety , amide , carboxylate , chemistry , catalysis , barium , substrate (aquarium) , cleavage (geology) , yield (engineering) , supramolecular chemistry , stereochemistry , polymer chemistry , organic chemistry , crystal structure , materials science , oceanography , fracture (geology) , metallurgy , composite material , geology
Five components spontaneously self‐assemble to yield the productive complex 1 , where one barium ion delivers an ethoxide to the carbonyl group of an amide substrate anchored by means of a distal carboxylate moiety to the other barium ion. High substrate specificity, fairly high reaction rates with catalytic turnover, and competitive inhibition by inert substrates are observed.