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Digitonin as a Chemical Trigger for the Selective Transformation of Giant Vesicles
Author(s) -
Menger Fredric M.,
Keiper Jason S.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19981231)37:24<3433::aid-anie3433>3.0.co;2-g
Subject(s) - vesicle , digitonin , cationic polymerization , chemistry , population , biophysics , lipid vesicle , biology , biochemistry , membrane , medicine , polymer chemistry , environmental health
The rupture of cationic giant vesicles (see the picture) in the presence of anionic vesicles, or the reverse, on exposure to digitonin is dependent on the respective cholesterol levels (0–50 mol%). Thus a disparate giant vesicle population can be chemically induced to release the contents from only a portion of its members.