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FT‐IR Mapping—A New Tool for Spatially Resolved Characterization of Polymer‐Bound Combinatorial Compound Libraries with IR Microscopy
Author(s) -
Haap Wolfgang J.,
Walk Tilmann B.,
Jung Günther
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19981217)37:23<3311::aid-anie3311>3.0.co;2-2
Subject(s) - characterization (materials science) , analyte , nanotechnology , spectroscopy , polymer , materials science , chemistry , combinatorial chemistry , computer science , organic chemistry , chromatography , physics , quantum mechanics
In the search for selective receptors , a promising approach is provided by immobilization of cyclopeptides on sensor surfaces (see picture) and subsequent detection of low molecular weight analytes with reflectometric interference spectroscopy (RIfS). Together with combinatorial chemistry, this innovative method offers a great potential for applications as sensors.