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Nucleic Acid Nanostructures and Topology
Author(s) -
Seeman Nadrian C.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19981217)37:23<3220::aid-anie3220>3.0.co;2-c
Subject(s) - polyhedron , nucleic acid , dna , topology (electrical circuits) , cube (algebra) , simplicity , nanotechnology , materials science , chemistry , physics , mathematics , geometry , combinatorics , biochemistry , quantum mechanics
Knots, polyhedra, and Borromean rings with specific structural and topological features can be made from DNA. Biotechnologists have been exploiting the programmability of DNA intermolecular associations for a quarter of a century. These operations have now been applied successfully to branched DNA species to produce complex target structures (for example, the cube shown in the picture) and a nanomechanical device. The assembly of two‐dimensional crystals with programmed topographic characteristics demonstrates the simplicity of translating design into surface structures.