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Solvent‐Free Organic Syntheses
Author(s) -
Metzger Jürgen O.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19981116)37:21<2975::aid-anie2975>3.0.co;2-a
Subject(s) - simplicity , biochemical engineering , yield (engineering) , organic solvent , solvent , chemistry , nanotechnology , combinatorial chemistry , organic chemistry , engineering , materials science , philosophy , chemical engineering , epistemology , metallurgy
Ecological points of view must nowadays be taken into consideration in the development of new syntheses and apportioned due importance in assessing the viability of a new synthesis. A crucial factor here is the need to restrict the use of ecologically harmful organic solvents. Examples are presented which show that solvent‐free reactions are not only of interest from an environmental viewpoint, but also offer considerable advantages in terms of yield, selectivity, and simplicity of the reaction procedures.

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