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A Tricyclic Polyamide Receptor for Carbohydrates in Organic Media
Author(s) -
Davis Anthony P.,
Wareham Richard S.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980904)37:16<2270::aid-anie2270>3.0.co;2-6
Subject(s) - chemistry , polyamide , amide , affinities , biphenyl , tricyclic , receptor , glycoside , methanol , stereochemistry , organic chemistry , combinatorial chemistry , biochemistry
The dissolution of glucose in chloroform is promoted by the receptor 1. Two biphenyl units and eight amide linkages line the cavity of 1 , which was designed for complementarity to β ‐glucopyranosyl. Receptor 1 binds octyl glycosides with unusual affinities and stereoselectivities, even with methanol present as cosolvent.