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A Short Synthesis of (±)‐Matrine
Author(s) -
Boiteau Laurent,
Boivin Jean,
Liard Annie,
QuicletSire Béatrice,
Zard Samir Z.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980504)37:8<1128::aid-anie1128>3.0.co;2-p
Subject(s) - matrine , xanthate , chemistry , intermolecular force , cascade , group (periodic table) , stereochemistry , molecule , polymer chemistry , organic chemistry , chromatography
Three different radical reactions were used in a short total synthesis of (±)‐matrine ( 1 ). Two of the four six‐membered rings and four new bonds were created in one radical cascade involving intermolecular addition followed by two successive cyclizations and transfer of a xanthate group.