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Protein Folding: A Perspective from Theory and Experiment
Author(s) -
Dobson Christopher M.,
Šali Andrej,
Karplus Martin
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980420)37:7<868::aid-anie868>3.0.co;2-h
Subject(s) - folding (dsp implementation) , protein folding , mechanism (biology) , perspective (graphical) , field (mathematics) , key (lock) , computer science , management science , cognitive science , chemistry , epistemology , data science , philosophy , artificial intelligence , engineering , psychology , mathematics , mechanical engineering , biochemistry , computer security , pure mathematics
The mechanism of protein folding (represented schematically below) is one of the most fascinating problems in the field of chemical reactions. This review presents the progess made recently in understanding key elements of this reaction and describes a solution to the often quoted Levinthal Paradox.