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The Total Synthesis of Eleutherobin: A Surprise Ending
Author(s) -
Chen XiaoTao,
Zhou Bishan,
Bhattacharya Samit K.,
Gutteridge Clare E.,
Pettus Thomas R. R.,
Danishefsky Samuel J.
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980403)37:6<789::aid-anie789>3.0.co;2-3
Subject(s) - stille reaction , total synthesis , surprise , natural product , trifluoromethanesulfonate , chemistry , stereochemistry , combinatorial chemistry , organic chemistry , communication , psychology , catalysis
An “sp 2 –sp 3 Stille coupling” of the vinyl triflate 1 and the stannyl compound 2 is a key step toward the completion of the total synthesis of eleutherobin, a natural product exhibiting taxol‐like cytotoxic activity.