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The Catalytic Enantioselective Construction of Molecules with Quaternary Carbon Stereocenters
Author(s) -
Corey Elias J.,
GuzmanPerez Angel
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980302)37:4<388::aid-anie388>3.0.co;2-v
Subject(s) - stereocenter , enantioselective synthesis , quaternary carbon , catalysis , molecule , sequence (biology) , quaternary , chemistry , stereochemistry , combinatorial chemistry , organic chemistry , paleontology , biology , biochemistry
A long‐standing challenge to synthesis can now be met through the use of new and powerful catalytic asymmetric reactions for the assembly of complex chiral molecules with quaternary stereocenters from achiral building blocks. The reaction sequence shown below is just one example discussed in this review.