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Evidence for C−H⋅⋅⋅O Hydrogen Bond Assisted Recognition of a Pyrimidine Base in the Parallel DNA Triple‐Helical Motif
Author(s) -
Marfurt Judith,
Leumann Christian
Publication year - 1998
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(19980202)37:1/2<175::aid-anie175>3.0.co;2-p
Subject(s) - uracil , pyrimidine , thymine , triple helix , motif (music) , hydrogen bond , chemistry , dna , cytosine , hypoxanthine , base pair , pyrimidine dimer , triple bond , nucleobase , stereochemistry , crystallography , biochemistry , dna damage , molecule , physics , enzyme , double bond , polymer chemistry , organic chemistry , acoustics
The efficient recognition of the pyrimidine base uracil by hypoxanthine or thymine in the parallel DNA triplex motif is based on the interplay of a conventional N−H⋅⋅⋅O and an unconventional C−H⋅⋅⋅O hydrogen bond.