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The Formation of Heterodimers by Vancomycin Group Antibiotics
Author(s) -
Staroske Thomas,
O′Brien Dominic P.,
J. D. Jørgensen Thomas,
Roepstorff Peter,
Williams Dudley H.,
Heck Albert J. R.
Publication year - 2000
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(20000204)6:3<504::aid-chem504>3.0.co;2-5
Subject(s) - electrospray ionization , chemistry , mass spectrometry , nuclear magnetic resonance spectroscopy , aqueous solution , spectroscopy , electrospray , vancomycin , crystallography , stereochemistry , chromatography , bacteria , physics , quantum mechanics , biology , genetics , staphylococcus aureus
The formation of heterodimers (see diagram) in mixtures of glycopeptide antibiotics are investigated by electrospray ionization mass spectrometry (ESI‐MS) and NMR spectroscopy. Dimerization constants are determined.

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