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Highly Efficient and Practical Optical Resolution of 2‐Amino‐2′‐hydroxy‐1,1′‐binaphthyl by Molecular Complexation with N ‐Benzylcinchonidium Chloride: A Direct Transformation to Binaphthyl Amino Phosphine
Author(s) -
Ding Kuiling,
Wang Yang,
Yun Hongying,
Liu Jinxia,
Wu Yangjie,
Terada Masahiro,
Okubo Yasutaka,
Mikami Koichi
Publication year - 1999
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19990604)5:6<1734::aid-chem1734>3.0.co;2-g
Subject(s) - resolution (logic) , phosphine , chemistry , salt (chemistry) , amino acid , solid state , alcohol , ligand (biochemistry) , chloride , stereochemistry , ammonium , ammonium chloride , polymer chemistry , organic chemistry , biochemistry , receptor , artificial intelligence , computer science , catalysis
A new type of N,P chiral ligand ( 1 ) was synthesized through a simple and practical resolution of racemic 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl ( 2 ) by molecular complexation in the solid state. The procedure represents the first example of the optical resolution of an amino alcohol with a chiral ammonium salt.