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Memory Effects in Pd‐Catalysed Allylic Alkylation: Stereochemical Labelling through Isotopic Desymmetrization
Author(s) -
LloydJones Guy C.,
Stephen Susanna C.
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19981204)4:12<2539::aid-chem2539>3.0.co;2-1
Subject(s) - desymmetrization , allylic rearrangement , tsuji–trost reaction , labelling , chemistry , alkylation , substrate (aquarium) , catalysis , stereochemistry , medicinal chemistry , organic chemistry , enantioselective synthesis , biology , biochemistry , ecology
The 13 C NMR analysis of 2 allows both memory effects in the Pd‐catalysed allylic alkylation of racemic (±)‐ 1 to be measured simultaneously without recourse to enantiomerically enriched substrate.