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Rare Keto‐Aldoses from Enzymatic Oxidation: Substrates and Oxidation Products of Pyranose 2‐Oxidase
Author(s) -
Freimund Stefan,
Huwig Alexander,
Giffhorn Friedrich,
Köpper Sabine
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19981204)4:12<2442::aid-chem2442>3.0.co;2-a
Subject(s) - pyranose , chemistry , enzyme , oxidase test , biochemistry , glucose oxidase , glycoside hydrolase , glycosyl , stereochemistry , organic chemistry
Enzymatic carbohydrate oxidation with pyranose oxidase converts a variety of carbohydrates into 2‐keto‐aldoses in yields from 40 to 98 % (see figure). Some glycosides may be regioselectively oxidised in position 3 by using the same enzyme, and pyranose oxidase can also act as a glycosidase/glycosyl‐transferring enzyme with some compounds. The structural requirements for substrates of pyranose oxidase are deduced.