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When Is a Proton Not a Proton?
Author(s) -
Trost Barry M.
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19981204)4:12<2405::aid-chem2405>3.0.co;2-0
Subject(s) - protonation , proton , catalysis , chemistry , metal , atom (system on chip) , computational chemistry , photochemistry , combinatorial chemistry , organic chemistry , ion , physics , computer science , nuclear physics , embedded system
In spite of the large number of protonated complexes , their use in catalytic cycles has been little explored. The existing examples suggest that catalytic processes initiated by the protonation of a low‐valent metal hold promise for the development of selective, efficient, and atom‐economical addition reactions under very mild conditions, if the protonation occurs with weak acids. The acidity required depends upon the basicity of the metal, and the latter can be increased by the use of more electron‐rich ligands (see figure).