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Synthesis of Oligosaccharide Dendrimers
Author(s) -
Colonna Barbara,
Harding Valerie D.,
Nepogodiev Sergey A.,
Raymo Françisco M.,
Spencer Neil,
Stoddart J. Fraser
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19980710)4:7<1244::aid-chem1244>3.0.co;2-8
Subject(s) - dendrimer , oligosaccharide , macromolecule , chemistry , molecular mass , stereochemistry , biophysics , polymer chemistry , biochemistry , biology , enzyme
As many as 21 D ‐glucopyranose residues have been incorporated into oligosaccharide dendrimers (right) in a convergent synthesis involving the blockwise contruction of oligosaccharide “wedges”, followed by their attachment to a central core component. These nanosized, highly branched macromolecules possess molecular diameters ranging between 5 and 6 nm and molecular weights in the order of 10000 Daltons.