Premium
New Catalytic Concepts for the Asymmetric Aldol Reaction
Author(s) -
Gröger Harald,
Vogl Erasmus M.,
Shibasaki Masakatsu
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19980710)4:7<1137::aid-chem1137>3.0.co;2-z
Subject(s) - aldol reaction , lewis acids and bases , catalysis , ketone , lewis acid catalysis , chemistry , transition metal , combinatorial chemistry , organic chemistry
New and highly efficient methods based on various catalytic concepts have recently been developed for the asymmetric aldol reaction. These include new transition metal based catalysts, creative approaches for activating the ketone, and the use of novel chiral nonmetallic Lewis acids and Lewis bases as catalysts, shown schematically on the right.