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Conformation Design of Hydrocarbon Backbones: A Modular Approach
Author(s) -
Hoffmann Reinhard W.,
Stahl Martin,
Schopfer Ulrich,
Frenking Gernot
Publication year - 1998
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/(sici)1521-3765(19980416)4:4<559::aid-chem559>3.0.co;2-t
Subject(s) - modular design , flexibility (engineering) , preference , hydrocarbon , chemistry , stereochemistry , computer science , computational chemistry , mathematics , organic chemistry , programming language , statistics
Full conformational flexibility and yet a high preference for a single backbone conformation is displayed by certain hydrocarbon skeletons such as the one on the right (calculated conformational preference >99%). The principles behind the design of such monoconformational structures are discussed here.