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New growth factors for imaginal discs
Author(s) -
Hipfner David R.,
Cohen Stephen M.
Publication year - 1999
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/(sici)1521-1878(199909)21:9<718::aid-bies2>3.0.co;2-z
Subject(s) - imaginal disc , biology , microbiology and biotechnology , drosophila melanogaster , drosophila (subgenus) , cell growth , chitinase , vertebrate , evolutionary biology , genetics , gene
Several families of peptide growth factors are implicated in regulating cell growth and proliferation of vertebrate cells in culture. Genetic studies in Drosophila implicate some of these factors in growth control in vivo. A recent report identifies a new family of growth factors, related to chitinase enzymes, required by Drosophila imaginal disc cells in culture. (1) It will be of interest to determine how such factors relate to size regulation during development. BioEssays 21:718–720, 1999. © 1999 John Wiley & Sons, Inc.