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Cell cycle control in the Drosophila wing
Author(s) -
Milán Marco
Publication year - 1998
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/(sici)1521-1878(199812)20:12<969::aid-bies1>3.0.co;2-l
Subject(s) - decapentaplegic , wing , biology , cell growth , drosophila (subgenus) , cell cycle , cell division , microbiology and biotechnology , cell , imaginal disc , genetics , drosophila melanogaster , gene , aerospace engineering , engineering
How Wingless and Decapentaplegic regulate cell proliferation in the developing Drosophila limbs and how cell proliferation and limb growth are coordinated are two of the most intriguing questions in developmental biology nowadays. Two recent reports [Johnston LA, Edgar BA. Nature 1998;394:82–84 (Ref. 1) and Neufeld TP, et al. 1998;Cell 93:1183–1193 (Ref. 2)] have shed new light on these questions. The first report [Johnston LA, Edgar BA. Nature 1998;394:82–84 (Ref. 1)] shows how Wingless regulates the cell cycle of a particular group of cells in the late wing discs. A second paper [Neufeld TP, et al. 1998;Cell 93:1183–1193 (Ref. 2)] shows the role of cell cycle regulators in proliferating wing disc cells and the relationship between cell division and limb growth. BioEssays 20:969–971, 1998. © 1998 John Wiley & Sons, Inc.