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Gene clusters and polycistronic transcription in eukaryotes
Author(s) -
Blumenthal Thomas
Publication year - 1998
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/(sici)1521-1878(199806)20:6<480::aid-bies6>3.0.co;2-q
Subject(s) - biology , gene , transcription (linguistics) , genetics , computational biology , gene expression , messenger rna , evolutionary biology , philosophy , linguistics
Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre‐mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants. BioEssays 20 :480–487, 1998. © 1998 John Wiley & Sons, Inc.