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Zeeman–Stark modeling of the RF EMF interaction with ligand binding
Author(s) -
Chiabrera A.,
Bianco B.,
Moggia E.,
Kaufman J.J.
Publication year - 2000
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/(sici)1521-186x(200005)21:4<312::aid-bem7>3.0.co;2-#
Subject(s) - zeeman effect , stark effect , physics , chemistry , nuclear magnetic resonance , atomic physics , magnetic field , electric field , quantum mechanics
The influence of radiofrequency electromagnetic exposure on ligand binding to hydrophobic receptor proteins is a plausible early event of the interaction mechanism. A comprehensive quantum Zeeman–Stark model has been developed which takes into account the energy losses of the ligand ion due to its collisions inside the receptor crevice, the attracting nonlinear endogenous force due to the potential energy of the ion in the binding site, the out of equilibrium state of the ligand–receptor system due to the basal cell metabolism, and the thermal noise. The biophysical “output” is the change of the ligand binding probability that, in some instances, may be affected by a suitable low intensity exogenous electromagnetic “input” exposure, e.g., if the depth of the potential energy well of a putative receptor protein matches the energy of the radiofrequency photon. These results point toward both the possibility of the electromagnetic control of biochemical processes and the need for a new database of safety standards. Bioelectromagnetics 21:312–324, 2000. © 2000 Wiley‐Liss, Inc.