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Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji)
Author(s) -
Lisi A.,
Pozzi D.,
Pasquali E.,
Rieti S.,
Girasole M.,
Cricenti A.,
Generosi R.,
Serafino A.L.,
CongiuCastellano A.,
Ravagnan G.,
Giuliani L.,
Grimaldi S.
Publication year - 2000
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/(sici)1521-186x(200001)21:1<46::aid-bem7>3.0.co;2-z
Subject(s) - lymphoblast , raji cell , magnetic field , field (mathematics) , immunology , biology , pathology , physics , medicine , cell culture , mathematics , genetics , quantum mechanics , lymphoma , pure mathematics
Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli‐like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. Bioelectromagnetics 21:46–51, 2000. © 2000 Wiley‐Liss, Inc.