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Micturitional disturbance in Wernicke's encephalopathy
Author(s) -
Sakakibara Ryuji,
Hattori Takamichi,
Yasuda Kosaku,
Yamanishi Tomonori,
Tojo Masaki,
Mori Masahiro
Publication year - 1998
Publication title -
neurourology and urodynamics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 90
eISSN - 1520-6777
pISSN - 0733-2467
DOI - 10.1002/(sici)1520-6777(1997)16:2<111::aid-nau4>3.0.co;2-h
Subject(s) - medicine , hyperreflexia , diplopia , ptosis , gait disturbance , ataxia , encephalopathy , thiamine , anesthesia , surgery , physical medicine and rehabilitation , psychiatry
A 24‐year‐old pregnant woman started to have hyperemesis gravidarum 6 weeks before admission. Four weeks later she had vertigo, diplopia, staggering gait, mild dyspnea, dysphagia, and incontinence of urine. On admission she presented with ophthalmoplegia, ptosis, ataxia, decreased tendon reflex, and memory disturbance. Brain magnetic resonance imaging revealed abnormal intensities in medial thalamic‐hypothalamic regions and the periaqueductal area, and she was diagnosed with Wernicke's encephalopathy. Urodynamic studies revealed decreased bladder volume and detrusor hyperreflexia. Six weeks after the administration of 100 mg/day of thiamine, urge incontinence gradually recovered, together with neurological signs. Lesions of the medial thalamic‐hypothalamic area and the periaqueductal gray matter seemed to be mainly responsible for micturitional disturbance in our patient with Wernicke's encephalopathy. Neurourol. Urodynam. 16:111–115, 1997. © 1997 Wiley‐Liss, Inc.