Premium
Use of the selective serotonin reuptake inhibitor citalopram in a possible animal analogue of obsessive‐compulsive disorder
Author(s) -
Stein Dan J.,
Mendelsohn Ivan,
Potocnik Felix,
Van Kradenberg Jeanine,
Wessels Charmaine
Publication year - 1998
Publication title -
depression and anxiety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.634
H-Index - 129
eISSN - 1520-6394
pISSN - 1091-4269
DOI - 10.1002/(sici)1520-6394(1998)8:1<39::aid-da8>3.0.co;2-0
Subject(s) - citalopram , serotonin reuptake inhibitor , serotonin uptake inhibitors , serotonin , reuptake inhibitor , obsessive compulsive , animal studies , pharmacology , psychology , medicine , psychiatry , fluoxetine , receptor
Canine acral lick dermatitis (ALD) has been suggested as an animal analogue of obsessive‐compulsive disorder (OCD). A series of dogs with ALD or similar conditions were treated with citalopram, the most selective of the selective serotonin reuptake inhibitors. Six of nine (66.7%) dogs showed significant improvement. Given the apparent efficacy of citalopram in the treatment of OCD and related disorders, these data provide further evidence that ALD is a useful animal analogue of OCD. Depression and Anxiety 8:39–42, 1998. © 1998 Wiley‐Liss, Inc.