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Transition metal complexes in organic synthesis, part 59. 1 First enantioselective total synthesis of lavanduquinocin, a potent neuronal cell protecting substance from Streptomyces viridochromogenes
Author(s) -
Knölker HansJoachim,
Baum Elke,
Reddy Kethiri R.
Publication year - 2000
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(2000)12:5/6<526::aid-chir40>3.0.co;2-f
Subject(s) - enantioselective synthesis , chemistry , carbazole , total synthesis , transition metal , combinatorial chemistry , alkaloid , stereochemistry , organic chemistry , catalysis
Using (R)‐propene oxide as a chiral building block a convergent enantioselective synthesis of the potent neuronal cell protecting alkaloid lavanduquinocin has been accomplished by the iron‐mediated one‐pot construction of the carbazole framework. Chirality 12:526–528, 2000. © 2000 Wiley‐Liss, Inc.