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On the calculation of gibbs energy corresponding to enantioselective interactions at a direct HRGC separation of enantiomers
Author(s) -
Krupcík Ján,
Spánik Ivan,
Oswald Peter,
Májek Pavol,
Skacáni Ivan,
Sandra Pat
Publication year - 2000
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(2000)12:3<130::aid-chir5>3.0.co;2-f
Subject(s) - chemistry , enantiomer , pentane , congener , gibbs free energy , halogen , enantioselective synthesis , gas chromatography , chromatography , stereochemistry , computational chemistry , thermodynamics , organic chemistry , catalysis , physics , alkyl
A novel procedure is proposed for the calculation of Gibbs energy corresponding to enantiospecific interactions of 2‐(2,4‐dinitrophenoxy)‐, 2‐phenoxy‐, and 2‐halogen‐n‐pentane enantiomers with a β‐cyclodextrin (ChirasilDex) stationary phase under gas chromatographic conditions. This energy is calculated from retention data as a difference between the Gibbs energy of an enantiomer and its corresponding achiral congener. The procedure for the determination of 2‐(2,4‐dinitrophenoxy)‐, 2‐phenoxy‐ and 2‐halogen‐ n‐pentane achiral congener retention data is discussed in detail. Chirality 12:130–138, 2000. © 2000 Wiley‐Liss, Inc.