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Base‐catalyzed epimerization of the butenolide in annonaceous acetogenins
Author(s) -
Yu Qian,
Wu Yikang,
Wu YuLin,
Xia LiJun,
Tang MinHua
Publication year - 2000
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(2000)12:3<127::aid-chir4>3.0.co;2-e
Subject(s) - butenolide , chemistry , epimer , lactone , acetogenin , stereochemistry , moiety , traditional medicine , annonaceae , medicine
Abstract The elusive epimerization process in the chiral butenolide moiety of Annonaceous acetogenins was examined under several sets of conditions commonly used for elimination leading to the α,β‐unsaturated lactone and the results provide practical guidance in choosing elimination conditions. Chirality 12:127–129, 2000. © 2000 Wiley‐Liss, Inc.