Premium
Optical resolution of glycerin sulfides and glycerin selenides on the chiral stationary phase of cellulose‐tris(3,5‐dimethylphenylcarbamate)
Author(s) -
Zhaowen Yu,
Shengxiang Jiang,
Xia Liu,
Liren Chen
Publication year - 1999
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1999)11:7<598::aid-chir13>3.0.co;2-5
Subject(s) - chemistry , tris , cellulose , phase (matter) , resolution (logic) , chiral stationary phase , chromatography , organic chemistry , biochemistry , artificial intelligence , computer science
Cellulose‐tris(3,5‐dimethylphenylcarbamate) was prepared after a reported method and was coated onto an aminopropylated mesopore spherical silica gel. The final product was used as a chiral stationary phase of high performance liquid chromatography for the enantioseparation of a series of glycerin sulfides and glycerin selenides. Mixtures of hexane and 2‐propanol were used as mobile phases. The effects of 2‐propanol concentration in the mobile phase on the retention and resolution were investigated. Some enantiomers of the glycerin monosulfides and monoselenides could be separated satisfactorily, but none of the disulfides could be separated. The structural features of the solutes that influence chiral separation were discussed. Chirality 11:598–601, 1999. © 1999 Wiley‐Liss, Inc.