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Therapeutic agent for treating dysuria (NC‐1800): Absolute configuration of the enantiomers
Author(s) -
Yoshida Shinichi,
Yamamoto Masao,
Aoki Yoshio,
Nohira Hiroyuki
Publication year - 1999
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1999)11:3<256::aid-chir13>3.0.co;2-#
Subject(s) - absolute configuration , chemistry , enantiomer , salt (chemistry) , tartaric acid , stereochemistry , absolute (philosophy) , fumaric acid , organic chemistry , citric acid , philosophy , epistemology
The absolute configuration of an enantiomer of the title compound, (±)‐1·fumaric acid salt, was determined by X‐ray crystallographic analysis of (+)‐1 [salt of (+)‐tartaric acid [(+)‐2]]. This salt for X‐ray crystallographic analysis was prepared by a simple method. The analysis of (+)‐1 [salt of (+)‐2] showed that this enantiomer has the 5‐ S and 1‐ R absolute configuration. The final R and R w values were 0.0614 and 0.0713, respectively. Chirality 11:256–260, 1999. © 1999 Wiley‐Liss, Inc.