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Chiral recognition of phthalides and lactams
Author(s) -
Pirkle William H.,
Spence Patrick L.
Publication year - 1998
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1998)10:5<430::aid-chir9>3.0.co;2-9
Subject(s) - chemistry , chirality (physics) , enantiomer , chiral stationary phase , aryl , series (stratigraphy) , computational chemistry , stereochemistry , organic chemistry , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark , paleontology , alkyl , biology
In concert with a larger study of the processes by which chiral stationary phase CSP 1 differentiates between enantiomers, we have investigated the chromatographic separation of the enantiomers of a series of aryl‐substituted heterocycles of systematically varied structure. A mechanistic picture of how these and similar resolutions occur is emerging. The mechanistic hypothesis described herein is of predictive value. Chirality 10:430–433, 1998. © 1998 Wiley‐Liss, Inc.