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Synthesis, circular dichroism, and absolute stereochemistry of 1,1′:4′,1′‐ternaphthalene compounds
Author(s) -
Harada Nobuyuki,
Hiyoshi Norie,
Vassilev Vassil P.,
Hayashi Tamio
Publication year - 1997
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1997)9:5/6<623::aid-chir33>3.0.co;2-o
Subject(s) - chemistry , enantiopure drug , chirality (physics) , circular dichroism , cotton effect , absolute configuration , phthalic acid , amide , stereochemistry , exciton , axial chirality , organic chemistry , enantioselective synthesis , chiral symmetry , catalysis , physics , quantum mechanics , quark , nambu–jona lasinio model
Enantiopure 1,1′:4′,1′‐ternaphthalene compounds were synthesized via enantioresolution of 1,1′:4′,1′‐ternaphthalene‐2,2′‐dimethanol (2) by the chiral phthalic acid amide method. The CD spectra of chiral 1,1′:4′,1′‐ternaphthalene compounds synthesized showed typical intense exciton split CD Cotton effects, from which the absolute stereochemistry of these 1,1′:4′,1′‐ternaphthalene compounds was unambiguously determined by the CD exciton chirality method. Chirality 9:623–625, 1997. © 1997 Wiley‐Liss, Inc.