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Stereoselective synthesis of some chiral α‐ferrocenyl carbenium ions
Author(s) -
Brunner Andreas,
Taudien Stefan,
Riant Olivier,
Kagan Henri B.
Publication year - 1997
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1997)9:5/6<478::aid-chir14>3.0.co;2-l
Subject(s) - carbocation , chemistry , enantiopure drug , chirality (physics) , lewis acids and bases , stereoselectivity , lewis acid catalysis , ion , stereochemistry , alcohol , catalysis , enantioselective synthesis , computational chemistry , medicinal chemistry , organic chemistry , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
The synthesis of chiral ferrocenyl carbocations is described starting from enantiopure orthosubstituted ferrocenylcarboxaldehydes. Secondary or tertiary carbocations have been prepared by ionization of an alcohol precursor. The stereochemistry of secondary α‐ferrocenylcarbenium ions has been defined. Preliminary tests as Lewis acid catalysts have been performed. Chirality 9:478–486, 1997. © 1997 Wiley‐Liss, Inc.